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Executive Vice Premier Li Keqiangs brother, Li Keming, has served as Deputy Director of the State Tobacco Monopoly Administration since 2003

During the next few years, outreach projects were introduced, such as Quit and win don t start [15] and a Smoke-free class competition [16] , which has been a nationwide project held annually since 1998

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Pharmacological mechanisms The pharmacodynamic mechanism of benzodiazepine tolerance and dependence is probably homoeostatic down regulation of gamma-aminobutyric acid and benzodiazepine receptors in the limbic system.(28) Once this has occurred, withdrawal of the drug results in a state of underactivity of pathways utilising gamma-aminobutyric acid with a pattern of unapposed neuronal excitation characteristic of benzodiazepine withdrawal(29) and anxiety states.(10) Similar brain mechanisms mediate the psychological and somatic symptoms of both conditions, which are in many respects inseparable